NCT03876327

Fecal Microbiota Transplantation As a Potential Treatment for Parkinson's Disease

Fecal Microbiota Transplantation As a Potential Treatment for Parkinson's Disease: A Pilot Study

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Soroka University Medical Center · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Accepted

Summary

this pilot study aims to further explore the potential usage of Fecal microbiota transplantation in treating constipation and possibly also motor symptoms in Parkinson's disease (PD) patients, and to increase understanding of the potential relationship between the identities of intestinal microbial communities and PD.

Detailed description

Fecal microbiota transplantation (FMT) is a technique in which intestinal microbiota are transferred from a healthy donor to the patient, with as primary goal to introduce - or restore - a stable and 'healthy' microbial community in the gut. Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor symptoms and Gastrointestinal dysfunction, in particular constipation, affects up to 80% of PD patients and may precede the onset of motor symptoms by years. this study include one group of PD patients that will receive FMT. two other groups will serve as controls: 1. PD patients that will not receive FMT 2. healthy people who live with PD patients in the same house and share similar surrounding

Conditions

• Parkinson Disease

Interventions

Type	Name	Description
PROCEDURE	fecal microbial transplantation	Fecal microbiota transplantation (FMT) is a technique in which intestinal microbiota are transferred from a healthy donor to the patient, with as primary goal to introduce - or restore - a stable and 'healthy' microbial community in the gut.

Timeline

• Start date: 2015-08-19
• Primary completion: 2019-12-30
• Completion: 2020-06-30
• First posted: 2019-03-15
• Last updated: 2020-08-05

Locations

1 site across 1 country: Israel