NCT03874117

Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 58 (actual)
• Sponsor: Palo Alto Veterans Institute for Research · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The study will determine the efficacy of twice weekly hemodialysis in patients with residual kidney function.

Detailed description

Hemodialysis patients who have residual kidney function will undergo two 4-week study (twice weekly versus thrice weekly hemodialysis) using a cross-over design. Blood, urine, and dialysate samples will be collected at the end of each study period to determine adequacy of treatment and to assess uremic solute levels. Participants will complete quality of life questionnaires and cognitive paper tests.

Conditions

• Hemodialysis
• Kidney Failure, Chronic

Interventions

Type	Name	Description
OTHER	Twice Weekly Hemodialysis then Thrice Weekly Hemodialysis	Twice weekly hemodialysis for 4 weeks, then thrice weekly hemodialysis for 4 weeks.
OTHER	Thrice Weekly Hemodialysis then Twice Weekly Hemodialysis	Thrice weekly hemodialysis for 4 weeks, then twice weekly hemodialysis for 4 weeks.

Timeline

• Start date: 2018-07-01
• Primary completion: 2024-09-01
• Completion: 2025-05-31
• First posted: 2019-03-14
• Last updated: 2025-09-03
• Results posted: 2025-09-03

Locations

3 sites across 1 country: United States