NCT03868111

Sufentanil as Adjuvant of Balanced Anesthesia

Comparison Between Sufentanil and Remifentanil as General Anesthetic Adjuvant

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (actual)
• Sponsor: Kangbuk Samsung Hospital · Academic / Other
• Sex: All
• Age: 19 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study was to compare the efficacy and safety between sufentanil and remifentanil as an adjuvant of balanced general anesthesia.

Detailed description

The investigators hypothesized that sufentanil would reduce postoperative pain than remifentanil without prolonging recovery times in minor laparoscopic surgery when administered equivalent antinociceptive doses during surgery. Intraoperative opioid administration for equivalent nociception-antinociception balance could be achieved via surgical pleth index (SPI)-guided analgesia. This study was designed to compare the efficacy and safety between sufentanil and remifentanil as an adjuvant of balanced anesthesia in patients undergoing laparoscopic cholecystectomy under SPI-guided opioid administration.

Conditions

• Anesthesia

Interventions

Type	Name	Description
DRUG	Sufentanil	The infusion rate of sufentanil is adjusted to achieve a surgical pleth index of 20-50 throughout the operative time.
DRUG	Remifentanil	The infusion rate of remifentanil is adjusted to achieve a surgical pleth index of 20-50 throughout the operative time.

Timeline

• Start date: 2019-11-04
• Primary completion: 2020-01-12
• Completion: 2020-01-12
• First posted: 2019-03-08
• Last updated: 2020-06-04

Locations

1 site across 1 country: South Korea