NCT03867058

Tradeoff Between Spatial and Temporal Resolution

Tradeoff Between Spatial Resolution of Neural Excitation and Temporal Rate Processing

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 53 (actual)
• Sponsor: East Carolina University · Academic / Other
• Sex: All
• Age: 15 Years
• Healthy volunteers: Accepted

Summary

In this study, investigators will examine how temporal rate processing might be affected when the width of neural excitation narrows. The manipulation of neural excitation width will be achieved for example by changing electrode configurations or stimulating single versus multiple electrodes simultaneously. Investigators will then measure if the extent to which rate processing is affected by spatially restricted stimulation can predict a subject's overall speech recognition and predict also whether the subject is likely to benefit from a focused electrode configuration. Lastly, investigators will introduce and test a novel current focusing strategy where current focusing is applied in a channel specific manner and quantify if this intervention improves speech recognition. The primary endpoint of the study is speech recognition, and the secondary endpoint is psychophysical sensitivity to stimulation rate change.

Conditions

• Deafness

Interventions

Type	Name	Description
BEHAVIORAL	Electrode selection/electrode configuration	Electrodes will be chosen based on their spatial tuning curves. Focused stimulation will be applied to electrodes with good temporal processing acuity.

Timeline

• Start date: 2019-10-01
• Primary completion: 2023-04-04
• Completion: 2023-04-04
• First posted: 2019-03-07
• Last updated: 2023-04-07

Locations

1 site across 1 country: United States