NCT03864380

Analysis of the Variation of the Retinal Vascularization After a Prolonged Effort

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 29 (actual)
• Sponsor: Fondation Ophtalmologique Adolphe de Rothschild · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The cardiovascular parameters of prolonged physical exercice have been studied, but very little data is available about the retinal vascularization. The eye allows in vivo visualization of micro-vascularisation and is considered as an excellent marker of general vascular condition. The marathon is an intense and prolonged exercise (running 42.195 km) in aerobic environment. Thus the investigators propose to study the vascular parameters of the retina, before and after this physical exercise. This will allow : 1) to collect information on the physiology of the retinal vascularization to prolonged effort, 2) to detect any retinal damage (haemorrhages, edema, occlusion ...), not known to date. The results may highlight vascular effects related to retinal hypoxia (venous tortuosity, haemorrhage, venous occlusion, hypoxic edema). Furthermore the results may urge prevention in this sport more and more democratized. the investigators hypothesized that prolonged physical exercice causes a change in retinal vascularization.

Conditions

• Retinal Vascular Disorder
• Sport Injury

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Color retinography	Non mydriatic color retinography within 1 month before and within 1 hour after the marathon
DIAGNOSTIC_TEST	OCT-A	Optical Coherence Tomography - Angiography within 1 month before and within 1 hour after the marathon
DIAGNOSTIC_TEST	Blood pressure measurement	Blood pressure measurement within 1 month before and within 1 hour after the marathon

Timeline

• Start date: 2019-03-15
• Primary completion: 2019-04-14
• Completion: 2019-05-06
• First posted: 2019-03-06
• Last updated: 2019-05-07

Locations

1 site across 1 country: France