NCT03863392

Oral Misoprostol Solution in Comparison to Vaginal Misoprostol in Induction of Labor

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Accepted

Summary

Induction of labour at term is a common obstetric intervention. Induction of labour is the artificial initiation of labour before its spontaneous onset for the purpose of delivery of the fetoplacental unit using mechanical or pharmacological methods. To determine the effects of oral misoprostol solution compared to vaginal misoprostol in induction of labour.

Detailed description

Patients recruited in the study will be primigravida at term with obstetric or medical indication for labour induction. These patients will be either booked attending antenatal clinic referred for induction of labour or emergency admissions in labour room. A total of 100 women will be randomly selected for the study. I. Women will be given 20 ml (20 µg) of misoprostol solution orally every 2 hourly until adequate uterine contractions occurred (3 contractions per 10 min lasting 30-40 s). II. The induction regimen included application of Vagiprost 25 µg tablet in the posterior fornix of the vagina every 4 h (up to 6 doses) after determination of the Bishop score.

Conditions

• Normal Vaginal Delivery

Interventions

Type	Name	Description
DRUG	Misoprostol	induction of labor

Timeline

• Start date: 2018-06-15
• Primary completion: 2018-11-29
• Completion: 2019-03-15
• First posted: 2019-03-05
• Last updated: 2019-03-05

Locations

1 site across 1 country: Egypt