NCT03862391

Does Low Flow Anesthesia Reduce Postanaesthetic Emergence Agitation?

Evaluation of the Effects of Low Flow Anesthesia on Pain and Agitation in Patients After Recovery

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Sakarya University · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

In this study, the investigators aimed to compare postanesthetic agitation in patients undergoing laparotomic gynecological surgery under general anesthesia using sevoflurane at a fresh gas flow rate of 2 L / min with fresh gas flow rate of 0.5 L / min.

Detailed description

Emergence agitation is a temporary state of mental anxiety that occurs during general anesthesia recovery. It is characterized by emergence agitation, hallucination, excitation, delusion and confusion. Increased hemorrhage due to hypertension may cause serious complications such as injury to the surgical site, patients' self-removal of surgical drains and catheters, and self-extubation. Due to these, emergence agitation results need for additional treatment, psychological stress and increased medical workload for patients and their families. Emergence agitation after general anesthesia in adult patients was reported up to 20%. However, the ratios are very wide. In our operating room, the investigators observed that patients with low flow anesthesia were less agitated in the recovery phase than patients with normal flow anesthesia. In our researches, the investigators have not found any studies on the agitation values of patients who underwent low flow anesthesia in the literature.

Conditions

• Agitated; State, Acute Reaction to Stress

Interventions

Type	Name	Description
DRUG	Analgesics	while patients are in the PACU after general anesthesia, if patients' VAS scores are higher than 3, we will give them 50 mg of deksketoprofen as analgesic.
DRUG	Antiemetics	while patients are in the PACU after general anesthesia, if patient' Nausea and vomiting scores are higher than 1, we will give them 4 mg of ondansetron

Timeline

• Start date: 2018-06-01
• Primary completion: 2019-11-01
• Completion: 2019-11-01
• First posted: 2019-03-05
• Last updated: 2020-03-18

Locations

1 site across 1 country: Turkey (Türkiye)