NCT03862352

Glasgow Natural History Study Of Covered Coronary Interventions

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 161 (actual)
• Sponsor: NHS National Waiting Times Centre Board · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Covered stents (CS) are a potentially lifesaving treatment for grade III coronary perforation but delivery can be challenging, and the long-term durability and safety including risk of acute stent thrombosis are unknown. The GNOCCI study aims to evaluate long term outcomes after coronary perforation including patients treated with covered stents.

Detailed description

Covered stents (CS) are a potentially lifesaving treatment for grade III coronary perforation but delivery can be challenging, and the long-term durability and safety including risk of acute stent thrombosis are unknown. Using an electronic data base, details of all coronary perforations are identified and anonymised patient and procedural details are recorded.Procedural major adverse cardiac events (pMACE) are defined as a composite of death, myocardial infarction, stroke, target vessel revascularization or cardiac surgery within 24 hours of the index procedure. Two independent cardiologists adjudicate outcomes and differences in opinion are resolved by consensus with a third cardiologist. The overall GNOCCI study aims are: 1. Evaluate procedural and long term outcomes after coronary perforation 2. Long term safety and clinical events in patients treated with covered stents.

Conditions

• Coronary Artery Perforation
• Coronary Stent Occlusion
• Stent Thrombosis

Interventions

Type	Name	Description
DEVICE	Covered coronary stent	Insertion of covered coronary stent as part of standard care

Timeline

• Start date: 2000-01-01
• Primary completion: 2020-01-01
• Completion: 2022-01-01
• First posted: 2019-03-05
• Last updated: 2022-10-19

Locations

1 site across 1 country: United Kingdom