NCT03860402

The Effect of Warm Local Anesthetic Solution on Epidural Anesthesia

The Effect of Warm Local Anesthetic Solution for Sensory Block on Epidural Anesthesia of Cesarean Delivery : a Randomized Controlled Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Hallym University Kangnam Sacred Heart Hospital · Academic / Other
• Sex: Female
• Age: 20 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The investigators are going to compare the onset and duration of nerve blockage with the use of pre-warmed (38°C) and room temperature (20°C) local anesthetic solutions (ropivacaine and fentanyl) on epidural anesthesia for cesarean section, and compare the incidence of complications such as hypotension, nausea and vomiting.

Detailed description

Spinal anesthesia has a shorter time to onset than epidural anesthesia, and the amount of local anesthetic administered is lower than that of epidural anesthesia, resulting in less systemic toxicity and superior block effect. However, there are disadvantage that it is difficult to control the block height and the incidence of hypotension is high. On the other hand, epidural anesthesia has the advantages of less sudden hypotension due to slow autonomic blockade, but it has a disadvantage that sensory nerve and motor nerve block time is delayed compared to spinal anesthesia. The degree of nerve block for cesarean section surgery requires a high level of anesthesia above the T6 level, so the frequency of hypotension is high due to rapid sympathetic block after spinal anesthesia. In this respect, hemodynamically stable epidural anesthesia is preferred when performing anesthesia for cesarean section. The investigators are going to compare the onset and duration of nerve blockage with the use of pre-warmed (38°C) and room temperature (20°C) local anesthetic solutions (ropivacaine and fentanyl) on epidural anesthesia for cesarean section, and compare the incidence of complications such as hypotension, nausea and vomiting.

Conditions

• Cesarean Section

Interventions

Type	Name	Description
OTHER	Temperature	temperature of drug

Timeline

• Start date: 2019-02-01
• Primary completion: 2019-12-31
• Completion: 2020-01-31
• First posted: 2019-03-01
• Last updated: 2020-03-06

Locations

1 site across 1 country: South Korea