NCT03858855

Inhaled Essential Oil Effect on Common QOL Concerns During Cancer Treatment

Inhaled Essential Oil Effect on Common Quality of Life Concerns During Cancer Treatment

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 248 (actual)
• Sponsor: Ohio State University Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This single-blind, randomized controlled trial studies how well inhaled essential oils work for common quality of life concerns in patients who are undergoing cancer treatment such as chemotherapy, targeted therapy, and/or immunotherapy given through the vein (intravenously). Aromatherapy using essential oils, such as ginger essential oil, German chamomile essential oil, and bergamot essential oil, may improve quality of life issues such as nausea, anxiety, loss of appetite, and fatigue in patients undergoing treatment for cancer.

Detailed description

PRIMARY OBJECTIVES: I. To determine if aromatherapy, specifically inhaled essential oil, is beneficial for side effects related to cancer treatments involving chemotherapy, targeted therapy, and/or immunotherapy administered intravenously. II. To describe the effect of inhaled ginger essential oil, German chamomile essential oil, and bergamot essential oil on nausea and anxiety of patients receiving chemotherapy, targeted therapy, and/or immunotherapy administered intravenously. III. To describe the effect of decreased levels of nausea and/or anxiety on levels of appetite and/or fatigue. IV. To evaluate the acceptability of using a personal inhalation bottle for inhalation of essential oils. OUTLINE: Patients are randomized to 1 of 4 groups. GROUP I: Patients inhale 7 drops of bergamot essential oil using a personalized inhalation bottle three times daily (TID) (morning, midday, and evening) for up to 7 days. Patients also use a journal to document symptoms, time of inhalation, and medication use TID for up to 7 days. GROUP II: Patients inhale 7 drops of chamomile essential oil and complete journal as in group I. GROUP III: Patients inhale 7 drops of ginger essential oil and complete journal as in group I. GROUP IV (CONTROL): Patients inhale 7 drops of almond essential oil and complete journal as in group I.

Conditions

• Gastrointestinal Cancer
• Neuroendocrine Carcinoma
• Skin Cancer

Interventions

Type	Name	Description
PROCEDURE	Aromatherapy and Essential Oils	Use bergamot essential oil
PROCEDURE	Aromatherapy and Essential Oils	Use chamomile essential oil
PROCEDURE	Aromatherapy and Essential Oils	Use ginger essential oil
PROCEDURE	Aromatherapy and Essential Oils	Use almond essential oil
OTHER	Subject Diary	Complete journal

Timeline

• Start date: 2019-02-18
• Primary completion: 2020-04-13
• Completion: 2020-04-13
• First posted: 2019-03-01
• Last updated: 2020-08-04

Locations

1 site across 1 country: United States