NCT03858049

Efficacy and Safety of Crinone Versus Combination Medication (ACCESS)

Comparison of Crinone ® Versus Combination Medication for Luteal Phase Support on the Ongoing Pregnancy Rate of Frozen-thawed Cycle in Chinese Population a Randomized, Interventional, Open-label, Phase IV, Single Center, Pilot Study (ACCESS)

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 172 (actual)
• Sponsor: Merck KGaA, Darmstadt, Germany · Industry
• Sex: Female
• Age: 20 Years – 38 Years
• Healthy volunteers: Not accepted

Summary

The study to compare to the efficacy and safety of Crinone versus combination medication in infertile women receive frozen-thawed embryo transfer (FET) in artificial cycles (AC).

Conditions

• Infertility

Interventions

Type	Name	Description
DRUG	Crinone	Participants received Crinone 8% (90 milligrams \[mg\] an intravaginal progesterone gel contained in a single use, one piece applicator) once daily in morning from the day of endometrial transformation (Day -5) until ongoing pregnancy was confirmed up to Day 63.
DRUG	Duphaston	Participants received 10 mg of Duphaston tablet orally twice a day from the day of endometrial transformation (Day -5) until ongoign pregnancy was confirmed up to Day 63.

Timeline

• Start date: 2019-05-31
• Primary completion: 2021-10-27
• Completion: 2021-10-27
• First posted: 2019-02-28
• Last updated: 2024-03-12
• Results posted: 2024-03-12

Locations

1 site across 1 country: China