Clinical Trials Directory

Trials / Completed

CompletedNCT03854019

Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington's Disease

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
20 (actual)
Sponsor
The University of Texas Health Science Center, Houston · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to assess efficacy and safety of dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg) in patients with irritability due to Huntington's disease.

Conditions

Interventions

TypeNameDescription
DRUGDextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg)DM/Q 20mg/10mg one capsule once daily for 1 week, followed by DM/Q 20mg /10 mg twice daily for subsequent 4 weeks, and finally DM/Q 20mg/10mg once daily for 7days.
DRUGPlaceboPlacebo once daily for 1 week, followed by placebo twice daily for subsequent 4 weeks, and finally placebo once daily for 7days.

Timeline

Start date
2019-08-05
Primary completion
2022-11-11
Completion
2022-11-11
First posted
2019-02-26
Last updated
2024-01-05
Results posted
2024-01-05

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03854019. Inclusion in this directory is not an endorsement.