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CompletedNCT03852342

Reactive Doses and Times During Oral Food Challenge to Peanut

Reactive Doses and Times During Oral Food Challenge (OFC) to Peanut

Status
Completed
Phase
Study type
Observational
Enrollment
262 (actual)
Sponsor
University Hospital, Montpellier · Academic / Other
Sex
All
Age
2 Years
Healthy volunteers
Not accepted

Summary

Peanut allergy is a growing public health problem in developed countries with more and more hospitalizations for anaphylaxis. It has been determined that sensitization to certain peanut proteins such as rAra h 2, is predictive of allergy and could predict the severity of reaction (anaphylaxis) during Oral food challenges (OFC). So far, consensual threshold for cutaneous test and IgE as predictor in the positivity of OFC have not been determined. Identification of reactive doses for OFC and phenotype of patients would help to personalize management of patients subgroups, with an optimal security.

Conditions

Timeline

Start date
2018-10-10
Primary completion
2019-02-28
Completion
2019-03-20
First posted
2019-02-25
Last updated
2019-04-18

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT03852342. Inclusion in this directory is not an endorsement.

Reactive Doses and Times During Oral Food Challenge to Peanut (NCT03852342) · Clinical Trials Directory