NCT03850886

Nicotinamide in Non-Alcoholic Fatty Liver Disease Patients

Evaluation of Efficacy and Safety of Nicotinamide in Non-Alcoholic Fatty Liver Disease Patients

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 61 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The purpose of the study is to evaluate the efficacy and safety of Niacinamide supplementation on clinical outcome of fatty liver patients having type II DM through measurement of the following before and after Niacinamide administration: Liver enzymes, Lipid profie, HOMA-IR, Oxidative stress markers and endothelial dysfunction marker. Fibroscan with CAP will be done at baseline and at the end of the trial. Also, Evaluation of quality of life of patients before and after Niacinamide administration using Chronic Liver Disease questionnaire.

Conditions

• Non Alcoholic Fatty Liver Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Niacinamide Oral Tablet	Nature's Life Niacinamide 1000 mg
DRUG	Antidiabetic	Metformin or Sulphonylurea

Timeline

• Start date: 2019-01-15
• Primary completion: 2019-08-07
• Completion: 2019-08-07
• First posted: 2019-02-22
• Last updated: 2020-01-22

Locations

1 site across 1 country: Egypt