NCT03849196

Effectiveness of Bisacodyl Suppository Agent for Dose Reduction of Low Dose PEG

Simultaneous Combination of Bisacodyl Suppository Agent and 1L Polyethylene Glycol Plus Ascorbic Acid is Not Inferior and Comfortable Regimen Compared With 2L Polyethylene Glycol Plus Ascorbic Acid: A Randomized Controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 168 (actual)
• Sponsor: Samsung Medical Center · Academic / Other
• Sex: All
• Age: 20 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Proper bowel cleansing before colonoscopy is an important factor to increase the detection rate of lesions. Low volume polyethylene glycol (PEG) plus ascorbic (PEG-Asc) has reduced the dosage of previous bowel preparation agent, but it still presents discomfort to patients. The aim of this study was to confirm the efficacy and convenience of volume reduction of PEG-Asc by adding bisacodyl suppository at the same day by compared with conventional 2L PEG-Asc.

Detailed description

Eligibility criteria: outpatients between the ages of 20 and 70 years, who were scheduled for colonoscopy between August 2017 and January 2018 Exclusion criteria: patients with a history of gastrointestinal tract surgery, inflammatory bowel disease, severe active colitis, underlying chronic kidney disease, or pregnancy. Outcome measures: the Boston Bowel Preparation Scale (BBPS)

Conditions

• Bowel Preparation

Interventions

Type	Name	Description
DRUG	2L PEG-Asc	PEG-Asc powder
DRUG	Bisacodyl 10Mg Suppository	bisacodyl 10 mg suppository
DRUG	1L PEG-Asc	PEG-Asc powder

Timeline

• Start date: 2017-07-31
• Primary completion: 2018-01-30
• Completion: 2018-01-30
• First posted: 2019-02-21
• Last updated: 2019-02-21

Locations

1 site across 1 country: South Korea