NCT03849183

Subcutaneous Nitroglycerin for Pediatric Radial Artery Cannulation

The Effect of Subcutaneous Nitroglycerin on the Success Rate of Arterial Catheterization in Pediatric Patients: a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 116 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 2 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of the study is to evaluate the vasodilative effect of subcutaneous nitroglycerin during ultrasound-guided radial artery cannulation in pediatric patients. The hypothesis of this study is that the subcutaneous nitroglycerin will increase the radial artery size and improve the first-attempt success rate of radial artery cannulation. This is a single-center, double-blind, randomized, placebo-controlled study comparing the effect of subcutaneous nitroglycerin and saline on radial artery cannulation in pediatric patients undergoing general anesthesia. Prior to the procedure, each patient will be randomized into either the control arm, saline, or study arm, nitroglycerin.

Conditions

• Arterial Line

Interventions

Type	Name	Description
DRUG	Nitroglycerin	Subcutaneous nitroglycerin injection to increase the first attempt success rate of radial artery cannulation in pediatric patients
DRUG	Normal saline	Subcutaneous normal saline injection to increase the first attempt success rate of radial artery cannulation in pediatric patients

Timeline

• Start date: 2019-03-20
• Primary completion: 2019-07-22
• Completion: 2019-07-22
• First posted: 2019-02-21
• Last updated: 2019-11-06

Locations

1 site across 1 country: South Korea