NCT03848247

The Effect of Experimental Neck Pain in Healthy Participants

The Effect of Experimental Neck Pain in Healthy Participants - The Transition From Acute to Ongoing Pain

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Aalborg University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This study investigates if/how an experimentally applied muscle pain/soreness, lasting for some days may affect brain activity, balance, movement patterns, muscle function and pain sensitivity in a healthy population

Detailed description

All included healthy volunteers will participate in test-sessions on 4 separate days over approximately 2 weeks. During the study participants will be randomised into and either a control group (injection of isotonic saline into a neck muscle) or neck pain group (injection of Nerve Growth Factor (NGF) into a neck muscle). Alle participants tested with regards to: Brain activity related to neck muscles will be estimated using TMS Balance will be tested using a force place Body movements will be recorded using 3D tracking Muscle activity will be estimated using electromyography (EMG)

Conditions

• Healthy
• Neck Pain

Interventions

Type	Name	Description
OTHER	Injection of Isotonic saline	Half the participants will be injected in a neck muscle with isotonic saline (Control group) and the other half will get NGF (Neck pain group).
OTHER	Injection of NGF	Half the participants will be injected in a neck muscle with NGF (Neck pain group).

Timeline

• Start date: 2019-01-21
• Primary completion: 2019-05-01
• Completion: 2019-05-01
• First posted: 2019-02-20
• Last updated: 2019-02-21

Locations

1 site across 1 country: Denmark