NCT03845179

GA 6: The Blood Glucose-lowering Effect of Glucose-dependent Insulinotropic Polypeptide

The Blood Glucose-lowering Effect of Glucose-dependent Insulinotropic Polypeptide

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: University Hospital, Gentofte, Copenhagen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will investigate if the effect of DPP-4 inhibitors is mediated in part by Glucose-dependent insulinotropic polypeptide.

Detailed description

A randomized, placebo controlled study. Using a GIP receptor antagonist, we will investigate the glucose lowering effect of GIP during treatment with DPP-4 inhibitors.

Conditions

• Type2 Diabetes

Interventions

Type	Name	Description
OTHER	Placebo	Saline infusion
OTHER	GIP receptor antagonist	Used for infusion on study days
DRUG	DPP-4 inhibitor	Oral administration of DPP-4 inhibitor in active treatment period
OTHER	Placebo tablet	Oral administration of placebo tablet in placebo treatment period

Timeline

• Start date: 2019-05-29
• Primary completion: 2020-02-28
• Completion: 2020-02-28
• First posted: 2019-02-19
• Last updated: 2021-03-16

Locations

1 site across 1 country: Denmark