NCT03843879

TAP Blocks vs. IV Lidocaine for Kidney Transplants

A Comparison of Transversus Abdominis Plane Blocks Versus Continuous Intravenous Lidocaine for Kidney Transplant Surgery

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 124 (estimated)
• Sponsor: Benaroya Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study will compare continuous intravenous lidocaine against single-injection transversus abdominis plane (TAP) block as a modality for postoperative analgesia in kidney transplant surgery.

Detailed description

This study is a non-inferiority trial designed to assess the analgesic efficacy of an intravenous (IV) lidocaine infusion against single-injection transversus abdominis plane (TAP) block in patients undergoing kidney transplant surgery. The investigators propose a study of 124 subjects randomized into two groups. The control group will receive a TAP block. The study group will receive a continuous IV lidocaine infusion. The investigators hypothesize that there will be no statistically significant difference in postoperative opioid consumption between the two groups in the first 24 hours.

Conditions

• Postoperative Pain

Interventions

Type	Name	Description
PROCEDURE	Transversus Abdominis Plane Block	Single-injection transversus abdominis plane block with 30 mL of 0.25% Bupivacaine with 1:400,000 epinephrine
DRUG	Intravenous Lidocaine	Continuous intravenous lidocaine infusion

Timeline

• Start date: 2019-04-01
• Primary completion: 2021-03-01
• Completion: 2021-09-01
• First posted: 2019-02-18
• Last updated: 2019-07-17

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study