NCT03843112

Modulating the Vaginal Microbiome After Implantation Failure

Modulating the Vaginal Microbiome After Implantation Failure A Randomized Placebo Controlled Study of Vaginal Lactobacilli Supplements

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 74 (actual)
• Sponsor: Zealand University Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 43 Years
• Healthy volunteers: Accepted

Summary

Vaginal microbiome has in studies shown a link with the outcome of fertility treatment. The investigators wish to determine if it is possible to change an unfavorable vaginal microbiome using lactobacilli loaded vaginal supplements.

Conditions

• Implantation Failure
• Infertility, Female
• Vaginal Flora Imbalance

Interventions

Type	Name	Description
DRUG	Vivag Plus	Contains two lactobacilli strains; l. gasseri and l. rhamnosus
DRUG	Placebo - Cap	Vaginal supplements

Timeline

• Start date: 2019-03-01
• Primary completion: 2021-01-05
• Completion: 2021-02-27
• First posted: 2019-02-15
• Last updated: 2021-03-23

Locations

1 site across 1 country: Denmark