Clinical Trials Directory

Trials / Completed

CompletedNCT03840174

Safety and Immunogenicity of the Human Cytomegalovirus (CMV) Vaccine (V160) in Healthy Japanese Men (V160-003)

A Phase I Randomized, Double-Blind, Placebo-controlled Study to Evaluate the Safety, Tolerability and Immunogenicity of V160 (Human Cytomegalovirus Vaccine) in Healthy Japanese Men

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
18 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
Male
Age
20 Years – 64 Years
Healthy volunteers
Accepted

Summary

The purpose of the study is to assess the safety and tolerability of a 3-dose regimen of V160 administered by intramuscular (IM) injection in healthy Japanese male participants by cytomegalovirus (CMV) serostatus. There is no formal hypothesis.

Conditions

Interventions

TypeNameDescription
BIOLOGICALV160V160 administered as a 0.5 mL (100 Units) IM injection containing 225 mcg aluminum phosphate adjuvant (APA)
OTHERPlaceboSaline solution (0.9% sodium chloride \[NaCl\] administered as a 0.5 mL IM injection

Timeline

Start date
2019-03-08
Primary completion
2019-11-07
Completion
2019-11-07
First posted
2019-02-15
Last updated
2023-05-06
Results posted
2021-11-15

Locations

1 site across 1 country: Japan

Regulatory

Source: ClinicalTrials.gov record NCT03840174. Inclusion in this directory is not an endorsement.