Clinical Trials Directory

Trials / Completed

CompletedNCT03839524

A Trial Evaluating TG4050 in Ovarian Carcinoma.

A Phase I Trial Evaluating a Mutanome-directed Immunotherapy in Patients With High Grade Serous Carcinoma (HGSC) of the Ovary, Fallopian Tube or Peritoneum.

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
64 (actual)
Sponsor
Transgene · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a multicenter, open-label, single arm phase I study evaluating the safety and tolerability as well as some activity parameters of TG4050 in patients with ovarian, fallopian or peritoneal serous carcinoma.

Conditions

Interventions

TypeNameDescription
DRUGTG4050Subcutaneous injections weekly for the first 6 weeks and then every 3 weeks.

Timeline

Start date
2019-12-09
Primary completion
2024-10-08
Completion
2024-10-08
First posted
2019-02-15
Last updated
2025-11-14
Results posted
2025-11-14

Locations

6 sites across 2 countries: United States, France

Regulatory

Source: ClinicalTrials.gov record NCT03839524. Inclusion in this directory is not an endorsement.