NCT03836508

Effect of Dialysis Membranes on Inflammatory and Immune Processes in Hemodialysis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Sisli Hamidiye Etfal Training and Research Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Double blinded, randomized controlled trial evaluating medium cut-off dialyzer compared to high flux dialyzer in ironic hemodialysis patients over a 6 months period with 3 months crossovers.

Conditions

• Kidney Failure
• Renal Insufficiency, Chronic
• Dialysis Related Complication

Interventions

Type	Name	Description
DEVICE	Medium cut-off	All the dialysis sessions in this arm will be performed with the medium cut-off membrane (MCO) manufactured by Baxter International Corp. membrane for three months. This membrane will exclusively be used in hemodialysis. After third month, all patients will be switched to high-flux membrane manufactured by Fresenius. Modalities of hemodialysis : Blood flow: 300-400 mL/min; Dialysate flow: 500-800 mL/min
DEVICE	High-Flux	All the dialysis sessions in this arm will be performed with the high-flux membrane manufactured by Fresenius for three months. This membrane will exclusively be used in hemodialysis. After third month, all patients will be switched to MCO manufactured by Baxter International Corp. Modalities of hemodialysis : Blood flow: 300-400 mL/min; Dialysate flow: 500-800 mL/min

Timeline

• Start date: 2018-09-01
• Primary completion: 2019-07-01
• Completion: 2019-07-01
• First posted: 2019-02-11
• Last updated: 2020-03-19

Locations

1 site across 1 country: Turkey (Türkiye)