Trials / Completed
CompletedNCT03834337
Treatment of Patients With Active Neurocysticercosis in Eastern Africa
Characteristics of Patients With Symptomatic Active Neurocysticercosis and Effect of Treatment on Symptoms, Lesions and Quality of Life in Resource-poor Rural Areas of Eastern Africa - TOPANA, a Multi-centre Prospective Cohort Study.
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 63 (actual)
- Sponsor
- Technical University of Munich · Academic / Other
- Sex
- All
- Age
- 10 Years
- Healthy volunteers
- Not accepted
Summary
This multi-centre prospective cohort study of symptomatic patients with active neurocysticercosis (NCC) aims to identify factors related to treatment success of anthelmintic therapy. Neurological symptom/sign and cyst resolution, quality of life, accuracy and performance of serological T. solium diagnostics and NCC-specific immunological parameter will be followed up at multiple time points in the study. The final assessment will be done six months after the end of anthelmintic treatment. This study aims to guide treatment of NCC in sub-Saharan Africa by identifying factors that are associated with treatment outcomes. The factors that cause some people to fail complete resolution of all cysts and/or symptoms/signs are unknown.
Conditions
Timeline
- Start date
- 2019-04-01
- Primary completion
- 2022-01-31
- Completion
- 2022-01-31
- First posted
- 2019-02-07
- Last updated
- 2023-11-30
Locations
1 site across 1 country: Tanzania
Source: ClinicalTrials.gov record NCT03834337. Inclusion in this directory is not an endorsement.