NCT03833895

The Phenylephrine vs. Norepinephrine Infusion Undergoing Cesarean Section

The Phenylephrine vs. Norepinephrine Infusion by Lidico Monitoring With Pregnancy Patients Undergoing Cesarean Section

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 238 (actual)
• Sponsor: China International Neuroscience Institution · Academic / Other
• Sex: Female
• Age: 20 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Compare 0.05 μg/kg/min Norepinephrine and 0.25 μg/kg/min phenylephrine effect on fetus and parturient during Cesarean Section

Detailed description

1. Compare 0.05 μg/kg/min Norepinephrine and 0.25 μg/kg/min phenylephrine and control group effect on parturient hemodynamic change (systolic blood pressure SBP, diastolic blood pressure DBP,mean arterial pressure MAP,heart rate HR) and on LIDICO-rapid monitoring ( stroke volume SV, systemic vascular resistance SVR, cardiac output CO) and peripheral vein (PV) blood gas during Cesarean Section. 2. Compare 0.05 μg/kg/min Norepinephrine and 0.25 μg/kg/min phenylephrine and control group effect on fetus by blood gas of the umbilical vein (UV), umbilical artery (UA),

Conditions

• Cesarean Section Complications

Interventions

Type	Name	Description
DRUG	Norepinephrine	0.05ug/kg/min Norepinephrine during Cesarean Section Operation
DRUG	Phenylephrine	0.25ug/kg/min phenylephrine during Cesarean Section Operation
DRUG	Ringer's Solution	3 ml/kg/min of LR was administrated according to standard weight.

Timeline

• Start date: 2019-02-20
• Primary completion: 2019-09-01
• Completion: 2019-09-02
• First posted: 2019-02-07
• Last updated: 2020-02-10

Locations

1 site across 1 country: China