NCT03833271

The Efficacy of Influenza Vaccine Program in Children With Juvenile Idiopathic Arthritis. A Single Centre Results From Hungary

The Investigation of Immune Function and the Effectiveness of Influenza Vaccine in Children With Juvenile Idiopathic Arthritis Compared to Healthy Control

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 62 (actual)
• Sponsor: University of Pecs · Academic / Other
• Sex: All
• Age: 3 Years – 18 Years
• Healthy volunteers: Accepted

Summary

The aim of our study is to compare the immune function of patient treated with DMARD (methotrexate), or tumor necrosis factor (TNF)-alpha inhibitor (adalimumab) to healthy children. The study consists of three parts. In each part physical examination and routine laboratory tests are done. At the first examination flow cytometry analysis is performed, after that the participants are immunized with influenza (3Fluart) vaccine. At part two and three further flow cytometry is carried out and seroconversion is measured.

Conditions

• Juvenile Idiopathic Arthritis

Interventions

Type	Name	Description
BIOLOGICAL	Influenza vaccine, Immune function	Comparing immune function and seroconversion after immunizing healthy children and juvenile idiopathic arthritis (JIA) children treated with different type of medication with influenza vaccine.

Timeline

• Start date: 2018-10-28
• Primary completion: 2019-09-30
• Completion: 2019-09-30
• First posted: 2019-02-06
• Last updated: 2020-06-17

Locations

1 site across 1 country: Hungary