NCT03832699

Oral Dydrogesterone vs. Vaginal Micronized Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer

Oral Dydrogesterone vs. Vaginal Micronized Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer: a Non-inferiority Randomized Clinical Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Wolfson Medical Center · Other Government
• Sex: Female
• Age: 18 Years – 39 Years
• Healthy volunteers: Accepted

Summary

The current trial is intended to assess the efficacy of oral versus vaginal progesterone for luteal support in frozen IVF cycles.

Detailed description

Progesteron is used for luteal phase support in IVF cycles. Progesterone can be administered vaginally and orally. Duphaston is an oral progesterone drug, which has recentlly been proven effective in fresh cycle IVF. Yet, less is known regarding its efficacy in frozen cycle IVF. Thus, the objective of our trial is to compare the efficacy of vaginal and oral progesterone in frozen IVF cycles.

Conditions

• ART

Interventions

Type	Name	Description
DRUG	Dydrogesterone 10 MG	Oral progesterone 10 mg TID
DRUG	Endometrin 100Mg Vaginal Insert	Vaginal Endometrin 100 mg twice daily

Timeline

• Start date: 2019-03-01
• Primary completion: 2021-10-01
• Completion: 2021-10-01
• First posted: 2019-02-06
• Last updated: 2020-10-08

Locations

1 site across 1 country: Israel