NCT03832322

Adenoma Miss Rate With Water Exchange vs Carbon Dioxide Colonoscopy

Water Exchange Colonoscopy Decreased Adenoma Miss Rates in the Right and Proximal Colon: An Observational Study Using A Tandem Colonoscopy Approach

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 176 (actual)
• Sponsor: Evergreen General Hospital, Taiwan · Academic / Other
• Sex: All
• Age: 20 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This was an observational study comparing consecutive group of WE and CO2 insufflation in terms of right and proximal colon AMR by tandem colonoscopy.

Detailed description

This was a prospective observational study to assess how WE colonoscopy would fit into clinical and research practices. We first observed whether optimal WE colonoscopy decreased the AMR in the right and proximal colon in a tandem approach. If WE did lower the AMR as compared with data in the literature, a randomized RCT deserves to be studied. For the calculation of sample size in the upcoming RCT, the AMR in the CO2 group would be collected. The differences of the AMRs in the right and proximal colon determined by tandem colonoscopy using WE or CO2 insufflation would then be compared.

Conditions

• Colonic Adenoma
• Water Exchange Colonoscopy

Interventions

Type	Name	Description
PROCEDURE	Water exchange colonoscopy	During back-to-back colonoscopy, the first examination was completed with water exchange during insertion and CO2 insufflation during withdrawal. The second examination was completed with CO2 insufflation during both the insertion and withdrawal.
PROCEDURE	CO2 insufflation colonoscopy	During back-to-back colonoscopy, the first examination was completed with CO2 insufflation during both the insertion and withdrawal. The second examination was also completed with CO2 insufflation during both the insertion and withdrawal.

Timeline

• Start date: 2018-07-09
• Primary completion: 2018-11-28
• Completion: 2018-11-28
• First posted: 2019-02-06
• Last updated: 2023-04-12
• Results posted: 2019-05-10

Locations

1 site across 1 country: Taiwan