NCT03831568

Mechanical Cough Augmentation in Children With NMD

Prevalence and Use of Mechanical Cough Augmentation in Children With Neuromuscular Disorders in Norway

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 72 (actual)
• Sponsor: Oslo University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study investigates the prevalence and use of mechanical insufflation - exsufflation (MI-E) in children with Neuromuscular disorders (NMD) in Norway. The NMD related prevalence of MIE use in Norway will be described and possible regional differences regarding use will be assessed.

Detailed description

Neuromuscular diseases (NMD) in children are severe, possibly life-threatening orphan conditions. Respiratory tract infections and lung complications are the main causes of increased morbidity and mortality. The use of mechanical cough augmentation with insufflation-exsufflation (MIE) is a strategy to treat and prevent. Possible major benefits are described, but optimal settings for best efficacy and comfort in children are not established. The main objective is to determine the prevalence and use of MIE among children with NMD in Norway. All children with NMD \< 18 years which has received a machine for MI-E will be invited to participate in the study. The participants will be asked to complete two questionnaires. In addition will information from the data card in the MI-E machines give information about use. The information will be linked to the National register for Long term mechanical ventilation.

Conditions

• Neuromuscular Diseases
• Children, Only
• Airway Clearance Impairment
• Cough

Timeline

• Start date: 2018-01-01
• Primary completion: 2019-01-31
• Completion: 2019-01-31
• First posted: 2019-02-06
• Last updated: 2019-09-06

Locations

1 site across 1 country: Norway