NCT03830970

Effect of Canned Beans of Multiple Varieties in Daily Amounts of 1 Cup and 1/2 Cup on Serum LDL Cholesterol and Other Cardiovascular Disease Risk Biomarkers in Adults With Elevated LDL Cholesterol

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 73 (actual)
• Sponsor: University of Guelph · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The Bean Study will examine the effects of consuming two daily amounts of canned beans of multiple varieties on fasting serum cholesterol profile in adults with elevated LDL cholesterol.

Detailed description

The Bean Study (TBS) is a a multi-centre, randomized, crossover design study which will examine the effects of consuming two daily amounts of canned beans of multiple varieties on fasting serum cholesterol profile in adults with elevated LDL cholesterol. Participants will consume daily amounts of 1 cup canned beans, ½ cup of canned beans and 1 cup of white rice for 4 weeks each, separated by minimum 4-week washout periods. At the start and end of each 4-week treatment period, fasting blood samples will be collected and analyzed for lipids, glucose insulin and short chain fatty acids (SCFAs). Fecal samples will also be collected and analyzed for SCFA, bile acids and gut microbiota. Body weight and BMI will be also be measured at the start and end as well as mid-way of each treatment period. Finally 3-day food records will be completed mid-way during each treatment period.

Conditions

• Hypercholesterolemia
• Cardiovascular Diseases

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Canned beans of multiple varieties	Daily rotation of different varieties of canned beans including black, navy, pinto, red kidney and white kidney
DIETARY_SUPPLEMENT	White Rice	Minute Rice Long Grain White Rice

Timeline

• Start date: 2019-03-05
• Primary completion: 2021-01-05
• Completion: 2021-01-05
• First posted: 2019-02-05
• Last updated: 2021-08-05

Locations

2 sites across 1 country: Canada