NCT03829618

Lidocaine Administration During Flexible Bronchoscopy and Endobronchial Ultrasound

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 29 (actual)
• Sponsor: Milton S. Hershey Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess if there is decrease in cough during flexible bronchoscopy and endobronchial ultrasound when different modes of lidocaine administration are used. The modes of administration being evaluated are topical, nebulized and atomized.

Conditions

• Bronchiectasis Adult
• Mediastinal Lymphadenopathy
• Pneumonia
• Chest--Diseases
• Infiltrates
• Bronchopulmonary Disease
• Cancer, Lung

Interventions

Type	Name	Description
DRUG	Topical lidocaine	1% lidocaine topically applied in 4 mL aliquots
DRUG	Nebuliser solution	2% lidocaine dose at 2 mg/kg (max 160 mg) applied via jet nebulizer
DRUG	Nebuliser Suspension	2% lidocaine dosed at 2 mg/kg (max 160 mg) applied via vibrating mesh nebulizer

Timeline

• Start date: 2019-04-01
• Primary completion: 2020-08-31
• Completion: 2020-08-31
• First posted: 2019-02-04
• Last updated: 2021-10-12
• Results posted: 2021-10-12

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study