Clinical Trials Directory

Trials / Completed

CompletedNCT03828617

Trial to Evaluate the Safety and Immunogenicity of 3 Lots of 20-valent Pneumococcal Conjugate Vaccine in Pneumococcal Vaccine-Naïve Adults

A PHASE 3, RANDOMIZED, DOUBLE-BLIND TRIAL TO EVALUATE THE SAFETY AND IMMUNOGENICITY OF 3 LOTS OF 20-VALENT PNEUMOCOCCAL CONJUGATE VACCINE IN PNEUMOCOCCAL VACCINE-NAÏVE ADULTS 18 THROUGH 49 YEARS OF AGE

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
1,710 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
18 Years – 49 Years
Healthy volunteers
Accepted

Summary

This is a Phase 3, randomized, double-blind study with a 4-arm parallel design. Adults 18 through 49 years of age with no history of pneumococcal vaccination will be randomized in a 2:2:2:1 ratio to receive a single dose of: 20vPnC Lot 1; 20vPnC Lot 2; 20vPnC Lot 3; or 13vPnC.

Conditions

Interventions

TypeNameDescription
BIOLOGICAL20vPnC20vPnC
BIOLOGICAL20vPnC20vPnC
BIOLOGICAL20vPnC20vPnC
BIOLOGICAL13vPnCPneumococcal conjugate vaccine

Timeline

Start date
2019-02-14
Primary completion
2019-10-09
Completion
2019-10-09
First posted
2019-02-04
Last updated
2020-11-23
Results posted
2020-11-04

Locations

21 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03828617. Inclusion in this directory is not an endorsement.