NCT03827694

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 400 (estimated)
• Sponsor: Arkansas Children's Hospital Research Institute · Academic / Other
• Sex: All
• Age: 120 Days – 21 Years
• Healthy volunteers: Not accepted

Summary

This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).

Conditions

• Pulmonary Invasive Fungal Infections
• Pulmonary Invasive Aspergillosis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Non-Invasive Testing for PIFI	galactomannan assay, fungal PCRs, cell-free next-generation DNA/RNA sequencing, RNAseq

Timeline

• Start date: 2018-10-30
• Primary completion: 2025-12-31
• Completion: 2026-12-31
• First posted: 2019-02-01
• Last updated: 2024-09-25

Locations

33 sites across 2 countries: United States, Canada