NCT03824301

Different Modes of Ventilation During Cardiopulmonary Bypass

Comparative Study Between Different Modes of Ventilation During Cardiopulmonary Bypass and Its Effect on Postoperative Pulmonary Dysfunction

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

66 patients divided into 3 groups with different modes of ventilation.

Detailed description

Sixty-six patients going through open-heart surgeries were included in the study, divided into 3 groups (P: pressure controlled ventilation, V: volume controlled ventilation, C: control) in accordance with the mode of ventilation. Patients studied for chest x-ray, lung ultrasound, arterial oxygen partial pressure to fractional inspired oxygen ratio (PaO2/FiO2), Alveolar-arterial oxygen gradient, static lung compliance and dynamic lung compliance, taken after induction of anesthesia, 1h post cardiopulmonary bypass, 1h after arrival to cardiac surgical unit.

Conditions

• Postoperative Pulmonary Dysfunction

Interventions

Type	Name	Description
DEVICE	Volume controlled ventilation	Changing modes of ventilation during cardiopulmonary bypass
DEVICE	Pressure controlled ventilation	Applying pressure controlled ventilation during cardiopulmonary bypass Period

Timeline

• Start date: 2017-01-22
• Primary completion: 2018-03-30
• Completion: 2018-11-20
• First posted: 2019-01-31
• Last updated: 2019-01-31

Locations

1 site across 1 country: Egypt