NCT03822520

Clinical Study to Evaluate Effect on QT/QTc Interval After Multiple Dose of Celecoxib

A Randomized, Open-label, Negative and Positive Control, Crossover Clinical Study to Evaluate Effect on QT/QTc Interval After Multiple Dose of Celecoxib in Healthy Adult Volunteers

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Samsung Medical Center · Academic / Other
• Sex: All
• Age: 19 Years – 40 Years
• Healthy volunteers: Accepted

Summary

This study is conducted to evaluate effect on QT/QTc Interval after multiple dose of celecoxib among healthy adult volunteers. It is randomized, open-label, negative and postive control, and crossover study. Volunteers will be mainly checked up through ECG to find out changes of QT/QTc interval during the study.

Conditions

• Qt Interval, Variation in

Interventions

Type	Name	Description
DRUG	Celecoxib	Celecoxib 400mg capsule
DRUG	Moxifloxacin	Moxifloxacin 400mg tablet
OTHER	Water	Pure water 150ml

Timeline

• Start date: 2017-06-30
• Primary completion: 2018-05-25
• Completion: 2018-05-25
• First posted: 2019-01-30
• Last updated: 2019-01-30

Locations

1 site across 1 country: South Korea