NCT03821584

Brain Perfusion Assessment in the Acute Phase of Migraine Aura

Brain Perfusion Assessment in the Acute Phase of Migraine Aura.

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 25 (actual)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to determine the proportion of patients with change in brain perfusion during the acute phase of migraine attack with aura.

Detailed description

Migraine is a benign and frequent disorder. Migraine aura consists in reversible focal neurological symptoms developing gradually during attack. Its diagnosis relies mainly on patient's history, clinical examination and exclusion of other possible secondary causes to explain transient neurological signs. Thus it can be difficult particularly during first attack or during attack without headache to differentiate migraine aura from transient ischemic stroke. Considering the difference of care management and prognosis, an early distinction of migraine aura based on imaging techniques will have a particular interest. MRI with diffusion, SWI, Flair 2D, ARM 3D TOF, ASL sequences' are routinely performed for the management of acute neurological deficit. Arterial spin labeling (ASL), as a MR perfusion method, will be used to describe brain perfusion during migraine aura. The study hypothesis is that hyperperfusion occurs in brain territories corresponding to the neurological symptoms during migraine aura.

Conditions

• Emergencies

Interventions

Type	Name	Description
OTHER	the difference of care management and prognosis, an early distinction of migraine aura based on imaging techniques will have a particular interest	the difference of care management and prognosis, an early distinction of migraine aura based on imaging techniques will have a particular interest

Timeline

• Start date: 2019-03-01
• Primary completion: 2021-06-22
• Completion: 2021-07-22
• First posted: 2019-01-30
• Last updated: 2021-09-17

Locations

1 site across 1 country: France