NCT03817073

Assessing Fatiguability of Tongue Muscles in MS

Assessing Fatiguability of Tongue Muscles and the Effect on Tongue Strength and Swallowing Pressures in Patients With Multiple Sclerosis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Thomas More Kempen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Multiple Sclerosis (MS) patients with subjective dysphagia will be tested for tongue strength fatigue using a strictly defined fatigue paradigm. A maximum of 40 sets will be performed, each set consisting of 5 repetitions of 80% of maximum isometric pressure (MIP) at the anterior tongue, followed by a MIP at the anterior tongue. Cut-off criteria are a MIP \<50% of the baseline MIP, pronounced subjective discomfort and/or exceeding the allocated test time of 30 minutes.

Detailed description

Eligibility is Mini-Mental State Exam-score (MMSE) \> 23, a Eating Assessment Tool-score (EAT-10) \> 3, or a Functional Oral Intake Scale-score (FOIS) \< 7, or failing the Yale Swallow Protocol.

Conditions

• Muscle Weakness
• Fatigue
• Multiple Sclerosis
• Deglutition Disorders
• Exertion; Excess

Interventions

Type	Name	Description
DEVICE	Iowa Oral Performance Instrument (IOPI)	Using biofeedback to attain repetitions of 80% of baseline MIP.

Timeline

• Start date: 2019-03-01
• Primary completion: 2021-07-01
• Completion: 2021-07-01
• First posted: 2019-01-25
• Last updated: 2019-01-25

Locations

1 site across 1 country: Belgium