Trials / Unknown
UnknownNCT03815903
Induction Chemotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
A Phase 3, Randomized, Open-label Clinical Trial of Induction Chemotherapy Followed by Chemoradiotherapy Versus Chemoradiotherapy in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma
- Status
- Unknown
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 434 (estimated)
- Sponsor
- Barretos Cancer Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The benefit of induction chemotherapy followed by chemoradiotherapy for locally advanced head and neck squamous cell carcinoma is unknown. The present study is investigating if this therapeutic strategy improve overall survival.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Induction chemotherapy | 3 cycles, each 21 days, of Cisplatin 80mg/m2 plus Paclitaxel 175mg/m2 |
| COMBINATION_PRODUCT | Chemoradiotherapy | Radiotherapy 70Gy convencional fractionation concomitant to 3 cycles, each 21 days, of Cisplatin 100mg/m2 |
Timeline
- Start date
- 2018-12-19
- Primary completion
- 2020-12-01
- Completion
- 2025-12-01
- First posted
- 2019-01-24
- Last updated
- 2019-07-18
Locations
1 site across 1 country: Brazil
Source: ClinicalTrials.gov record NCT03815903. Inclusion in this directory is not an endorsement.