Clinical Trials Directory

Trials / Active Not Recruiting

Active Not RecruitingNCT03815643

Avelumab Program Rollover Study

An Open-Label, Multicenter Follow-up Study to Collect Long-term Data on Participants From Multiple Avelumab (MSB0010718C) Clinical Studies

Status
Active Not Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
205 (actual)
Sponsor
EMD Serono Research & Development Institute, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The main purpose of this study is to monitor the safety and tolerability of avelumab in participants with solid tumors who continue treatment with avelumab under the same treatment regimen as in the parent avelumab study.

Conditions

Interventions

TypeNameDescription
DRUGAvelumabParticipants entering this roll over study will receive avelumab as a 1-hour intravenous (IV) infusion at 10 milligram per kilogram (mg/kg) once every 2 weeks until progressive disease, according to respective parent studies (EMR100070-001, EMR100070-002, EMR100070-004 and EMR100070-008).

Timeline

Start date
2019-03-22
Primary completion
2026-08-21
Completion
2026-08-21
First posted
2019-01-24
Last updated
2026-03-31

Locations

104 sites across 22 countries: United States, Argentina, Australia, Belgium, Brazil, Bulgaria, Czechia, France, Germany, Hungary, Italy, Japan, Mexico, Poland, Romania, Russia, South Korea, Spain, Thailand, Turkey (Türkiye), Ukraine, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT03815643. Inclusion in this directory is not an endorsement.