NCT03814031

Hepatic Vein Flow During Orthotopic Liver Transplantation as Predictive Factor for Postoperative Graft Function

Hepatic Vein Flow Assessment With Transesophageal Echocardiography for Postoperative Graft Function Prediction in Orthotopic Liver Transplantation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 97 (actual)
• Sponsor: Henry Ford Health System · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Hepatic vein flow (HVF) assessment using transesophageal echocardiography (TEE) has a potential to predict postoperative graft function in orthotopic liver transplant (OLT). Investigators will measure HVF using TEE and assess the correlation with postoperative graft function indices such as early allograft dysfunction(EAD), prolonged INR, platelet, and total bilirubin.

Detailed description

During OLT, intraoperative TEE assessment of HVF (systolic and diastolic) were measured, and adjusted with donor graft weight. This index, HVF index, was assessed for correlation with EAD. HVF was calculated with hepatic vein area (cm2) x hepatic vein velocity (ml/s) in systole and diastole during the neohepatic phase. Investigators did ROC analysis to assess the predictive power for EAD, prolonged INR, platelet, and total bilirubin.

Conditions

• Postoperative Graft Function

Interventions

Type	Name	Description
OTHER	NO internvention	NO internvention

Timeline

• Start date: 2018-02-20
• Primary completion: 2019-12-31
• Completion: 2019-12-31
• First posted: 2019-01-23
• Last updated: 2024-09-23
• Results posted: 2024-09-23

Locations

1 site across 1 country: United States