NCT03813758

Inter-observer and Intra-observer Variability of the Wrinkle Test

Inter-observer and Intra-observer Variability of the Wrinkle Test and the Optimum Time Need for the Test. Pilot Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: HaEmek Medical Center, Israel · Academic / Other
• Sex: All
• Age: 2 Years – 100 Years
• Healthy volunteers: Accepted

Summary

Skin wrinkling of the fingers following immersion in warm water depends on intact sympathetic innervation. It is abolished by lesions affecting both central and peripheral sympathetic pathways. It affords a simple and reliable clinical test of sympathetic function.

Detailed description

Fingertip skin wrinkling after prolonged immersion in water is a well-recognized phenomenon, whereas a denervated digit does not exhibit normal skin wrinkling while a finger with a regenerated or repaired nerve shows at least partial reappearance of wrinkling. This is the basis for the bedside immersion-wrinkling test of autonomic digital nerve function. The exact mechanism of fingertip skin wrinkling is still subject to controversy. the purpose of this study is to examine the Inter-observer and Intra-observer Variability of the Wrinkle Test.

Conditions

• Wrinkle Test

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	wrinkle test	soaking in 40 deg water for 40 min. every 10 min the hand will be photo

Timeline

• Start date: 2019-09-15
• Primary completion: 2020-01-01
• Completion: 2020-01-01
• First posted: 2019-01-23
• Last updated: 2019-08-07

Locations

1 site across 1 country: Israel