NCT03811964

Photomotor Reflex to Evaluate the Role of the Non-visual Effects of Light in Neurological, Psychiatric and Ophthalmological Pathologies

Study of the Photomotor Reflex to Evaluate the Role of the Non-visual Effects of Light in Neurological, Psychiatric and Ophthalmological Pathologies

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 726 (estimated)
• Sponsor: University Hospital, Strasbourg, France · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The light has visual and non-visual effects on organism and can act on the behavior, the mood, the cognition and the sleep. These effects are mediated by "classical" retina photoreceptors which allow vision (rods, cones) but also melanopsin cells. The non-visual effects of light seems to be altered in many neurological, psychiatric or ophtalmological conditions but their exact role in the pathogenesis remains poorly understand. The purpose of the study is to increase our knowledge of the non-visual effects of light and establish new therapeutic applications

Conditions

• Sleep Disorders
• Neurological Pathologies
• Psychiatric Pathologies
• Ophthalmological Pathologies

Interventions

Type	Name	Description
OTHER	Specific light exposures	Specific light exposures using light in a wide range of intensities or different light/dark regimens

Timeline

• Start date: 2020-01-22
• Primary completion: 2027-01-01
• Completion: 2027-02-01
• First posted: 2019-01-22
• Last updated: 2025-08-08

Locations

1 site across 1 country: France