NCT03811717

Fasting and Exercise-induced Changes in Human Skeletal Muscle

Impact of Exercise-induced Energetic Stress During an 8-hour Fast on Metabolic Regulation in Resting Human Skeletal Muscle

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Queen's University · Academic / Other
• Sex: Male
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

This study examines the impact of increasing energetic stress during an 8-hour fast on metabolic pathways in human skeletal muscle. Specifically, participants will undergo two 8-hour fasting sessions in a randomized crossover fashion, with the addition of low-intensity arm exercise in one of the sessions. Changes in metabolic pathways will be examined in resting (leg) muscle before, during, and after the fast.

Conditions

• Skeletal Muscle Energetics

Interventions

Type	Name	Description
OTHER	FAST+EX	Participants will perform 2-hours of low-intensity arm exercise (8 x 15 min bouts of arm ergometer exercise separated by 10 min of rest) during an 8-hour fast.
OTHER	FAST	Participants will complete an 8-hour fast.

Timeline

• Start date: 2019-01-14
• Primary completion: 2019-04-30
• Completion: 2019-04-30
• First posted: 2019-01-22
• Last updated: 2019-05-30

Locations

1 site across 1 country: Canada