NCT03810040

Effect of Degranulation Needle With Different Diameters on the Rate Good Embryo in IVF

Effect of Degranulation Needle on the Rate Good Embryo in IVF

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 400 (estimated)
• Sponsor: Tang-Du Hospital · Academic / Other
• Sex: Female
• Age: 22 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality. To investigate the effect of denuding pipette in IVF outcomes, we plan to recruit women undergoing IVF treatment cycles and classified them into two groups according to the different diameters. Consequently, the rate of fertilization, zygotes cleaved, top quality embryos on D3, and blastocysts obtained were recorded.

Detailed description

Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality. To investigate the effect of denuding pipette in IVF outcomes, we plan to recruit women undergoing IVF treatment cycles and classified them into two groups according to the different diameters. The participants were divided into two group. Odd-numbered days the zygotes were degranulated with the 140 microns needles. Even-numbered days the zygotes were degranulated with the 150 microns needles. Consequently, the rate of fertilization, zygotes cleaved, top quality embryos on D3, and blastocysts obtained were recorded.

Conditions

• Embryo

Interventions

Type	Name	Description
DEVICE	140 microns denuding pipette	the degranulated needle size was 140 microns
DEVICE	150 microns denuding pipette	the degranulated needle size was 150 microns

Timeline

• Start date: 2019-02-01
• Primary completion: 2019-05-01
• Completion: 2019-11-01
• First posted: 2019-01-18
• Last updated: 2019-01-18

Locations

1 site across 1 country: China