NCT03808532

Moisturizer to Prevent Atopic Dermatitis

A Prospective Randomized Open-label Controlled Study to Assess Whether Daily Application of Skin Moisturizer Containing Acemannan Hydrogel From Birth Can Prevent Atopic Dermatitis in Children

• Status: Withdrawn
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: MYOR Ltd. · Industry
• Sex: All
• Age: 24 Hours – 120 Hours
• Healthy volunteers: Accepted

Summary

Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder associated with a decreased ability of the skin to function as an efficient immunological barrier. The disease is now two to three times more prevalent in children than it was just four decades ago. It is manifested by eczematous skin lesions associated with severe itch, leading to a significant impairment in quality of life. Of additional importance, AD oftentimes progresses to allergic rhinitis and/or asthma, a process referred to as the "atopic march." Recent reports have indicated that daily application of moisturizing creams on neonates and infants can prevent the occurrence of AD and subsequently food allergies. This is postulated to be the outcome of restoring the barrier integrity of the skin through the daily application of moisturizer.

Conditions

• Dermatitis, Atopic

Interventions

Type	Name	Description
OTHER	Cura+ Moisturizing Cream	Parents of at-risk infants in the intervention arm will be instructed to apply moisturizer to the infant's entire body once daily for six months.

Timeline

• Start date: 2020-06-01
• Primary completion: 2021-12-01
• Completion: 2022-12-01
• First posted: 2019-01-17
• Last updated: 2021-01-15