Trials / Unknown
UnknownNCT03807986
The Combination Therapy of Nanofat Grafting and PRP Compared With Microfat Grafting and PRP Synergy in Treating Striae Distensae
The Combination Therapy of Nanofat Grafting and Platelet-Rich Plasma Injection Compared With Microfat Grafting and Platelet-Rich Plasma Injection Synergy in Treating Striae Distensae
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 12 (estimated)
- Sponsor
- First Affiliated Hospital of Jinan University · Academic / Other
- Sex
- All
- Age
- 18 Years – 35 Years
- Healthy volunteers
- Not accepted
Summary
Striae distensae is caused by the fracture and damage of the elastic fibers and collagen fibers, which is still a difficulty to overcome. Based on the studies demonstrated that platelet-rich plasma(PRP) has positive effect on superficial scar, and nanofat and microfat are effective in treating atrophic scar. So in this clinical trial, the investigators are going to treat striae distensae by using two combination therapies. One is nanofat grafting and PRP injection synergy, and the other one is treated by microfat grafting with PRP injection.
Detailed description
The participants were randomly assigned into two groups. Group A is treated by nanofat grafting once every three months for 2 times combined with PRP injection once a month for 6 times. Group B will be treated by microfat grafting onceevery three months for 2 times combined with PRP injection once a month for 6 times. The participants were asked to come back 1、3、6、9 months after treatment for further follow-up.Before and after the treatment, the striae distensae will be assessed subjectively by satisfaction assessment, and objectively by ultrasound and immunohistochemical analysis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Nanofat grafting | Nanofat grafting will be applied once every three months for 2 times. |
| PROCEDURE | Microfat grafting | Microfat grafting will be applied once every three months for 2 times. |
| PROCEDURE | Platelet-rich plasma (PRP) Injection | PRP Injection will be applied once a month for 6 times. |
Timeline
- Start date
- 2019-02-01
- Primary completion
- 2019-05-01
- Completion
- 2020-12-31
- First posted
- 2019-01-17
- Last updated
- 2019-01-17
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03807986. Inclusion in this directory is not an endorsement.