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UnknownNCT03807583

Plasma Amino Acid Levels After Protein Ingestion or Amino Acid Injection During Dialysis

Prospective, Monocentric, Open-label, Randomized Study Comparing Intradialytic Plasma Kinetics of Amino Acids After Administration Per os of Renoral® and Intravenous Administration of Amino Acids.

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
30 (estimated)
Sponsor
Indigo Therapeutics · Industry
Sex
All
Age
18 Years – 100 Years
Healthy volunteers
Not accepted

Summary

The aim of the study is to compare intradialytic plasma kinetics of amino acids after administration per os of Renoral or intravenous administration of amino acids in patients with end-stage renal disease treated with hemodialysis maintenance.

Conditions

Interventions

TypeNameDescription
DRUGAminoven 10%After randomization to the visit Day 60, two months after patients inclusion (Visit Day 0) and one month after clinical examination (Visit Day 30), patients will be assigned to a group: * group A: RENORAL® product * group B: AMINOVEN® 10% product * group C: control group (without intradialytic supplementation) Patients will consume the products and will be followed for 3 months, one visit per month (Day 90, Day 120, Day 150). Protocol visits are included in the patient's course of care.
DIETARY_SUPPLEMENTRENORALAfter randomization to the visit Day 60, two months after patients inclusion (Visit Day 0) and one month after clinical examination (Visit Day 30), patients will be assigned to a group: * group A: RENORAL® product * group B: AMINOVEN® 10% product * group C: control group (without intradialytic supplementation) Patients will consume the products and will be followed for 3 months, one visit per month ( V3, V4, V5). Protocol visits are included in the patient's course of care.

Timeline

Start date
2019-03-15
Primary completion
2020-01-01
Completion
2020-07-01
First posted
2019-01-17
Last updated
2019-03-19

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT03807583. Inclusion in this directory is not an endorsement.