NCT03804710

To Evaluate the Effect of Moisturizing Creams on Skin Barrier Function

A Clinical Study to Investigate the Effects of Two Developmental Cosmetic Moisturizing Cream Formulations on the Barrier Function of Human Skin on the Face and Legs

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 158 (actual)
• Sponsor: GlaxoSmithKline · Industry
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to evaluate the impact of twice-daily topical application of two different moisturizing creams on skin barrier function for 4 weeks.

Detailed description

This study will be a randomized, evaluator-blind, single-center, two-treatment regimen, controlled, parallel-group, with a treatment period of 4 weeks. The study will assess the skin barrier function of the two-treatment regimen in healthy participants with dry, sensitive skin on the face and lower legs. All participants will be centrally randomized to one of the 2 treatment groups using an Interactive Response Technology (IRT).

Conditions

• Dry Skin
• Skin Care

Interventions

Type	Name	Description
DRUG	Developmental moisturizing cream 1	Participants will topically apply developmental moisturizing cream 1
DRUG	Developmental moisturizing cream 2	Participants will topically apply developmental moisturizing cream 2
OTHER	Standard cleanser soap	Participants will cleanse the entire face and both lower legs (between the knees and the ankles)with simple pure soap

Timeline

• Start date: 2019-01-22
• Primary completion: 2019-04-16
• Completion: 2019-04-16
• First posted: 2019-01-15
• Last updated: 2020-06-04
• Results posted: 2020-06-04

Locations

1 site across 1 country: Germany