NCT03803449

Patient Satisfaction and Safety With Propofol Based Sedation With or Without Fentanyl for Gastrointestinal Endoscopy

Patient Satisfaction and Safety With Propofol Based Sedation With or Without Fentanyl for Gastrointestinal Endoscopy :a Prospective ,Randomized ,and Cohort Study

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 500 (estimated)
• Sponsor: Shandong University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Patient satisfaction and safety with propofol based sedation with or without fentanyl for gastrointestinal endoscopy

Detailed description

This study divide patients into two groups, one will be given propofol midazolam and fentanyl; another group was given propofol with midazolam without fentanyl; to observe two groups of patients blood pressure, body movement, and propofol dosage , and the difference in operator satisfaction, and how many people need to give fentanyl again; and two groups of patients after the operation of the reaction, if there are dizziness, nausea, and other adverse reactions; finally, the differences of these two schemes in different populations were analyzed, and the rationalization and individualized medication will be put forward.

Conditions

• Patient Satisfaction

Interventions

Type	Name	Description
DRUG	50-200mg propofol	participants in both groups are given standard regimen including 50-200mg propofol.
DRUG	50ug fentanyl	participants in fentanyl group are given intervention regimen: 50ug fentanyl.
DRUG	1 mg midazolam	participants in both groups are given standard regimen including 1 mg midazolam.

Timeline

• Start date: 2019-01-01
• Primary completion: 2019-07-30
• Completion: 2019-10-30
• First posted: 2019-01-14
• Last updated: 2019-01-14