Clinical Trials Directory

Trials / Completed

CompletedNCT03800030

Effect of Cross Frequency tACS on Cognitive Control

A Pilot Study Investigating the Effects of Cross Frequency Transcranial Alternating Current Stimulation on Cortical Oscillations Underlying Cognition

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
26 (actual)
Sponsor
University of North Carolina, Chapel Hill · Academic / Other
Sex
All
Age
18 Years – 35 Years
Healthy volunteers
Accepted

Summary

Investigation of frequency specific transcranial alternating current stimulation on cognitive control signals in frontal cortex

Detailed description

Previous evidence suggests that there are specific frequency bands associated with different aspects of cognitive control. In specific delta (2-4Hz) and beta (15-30Hz) are associated with increased levels of abstraction for learned rules; and theta (5-8Hz) and gamma (30-50Hz) has been associated with increased set-size or number of learned rules. Here we aim to find causal evidence in support of these previous correlational findings by applying cross-frequency transcranial alternating current stimulation (tACS) in the specific frequency bands previously shown to be task-relevant. In a crossover design, we stimulate subjects with either delta-beta or theta-gamma tACS during performance of a hierarchical cognitive control task that manipulates the level of abstraction and set-size of rules that must be learned in order to make the correct button press.

Conditions

Interventions

TypeNameDescription
DEVICETheta-gamma tACSNeuroConn technologies, direct current-stimulator plus
DEVICEDelta-beta tACSNeuroConn technologies, direct current-stimulator plus
DEVICESham tACSNeuroConn technologies, direct current-stimulator plus

Timeline

Start date
2018-10-07
Primary completion
2019-07-25
Completion
2019-07-25
First posted
2019-01-10
Last updated
2020-05-18
Results posted
2020-05-18

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03800030. Inclusion in this directory is not an endorsement.